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October 2017: What’s New in Research

Psoriasis; combined immunotherapy; genetic cause for erythropoietic protoporphyria

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A Portal Opens for Clinical Trial Recruitment

The Partners Research Portal offers investigators a new way to share their clinical trials and recruit participants from among the site’s nearly 40,000 visitors

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Research Rumble: A Communication Battle of the Science Stars

Five investigators from BWH and MGH shared their research with the general public as part of the Cambridge Science Festival’s first-ever Research Rumble competition

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Artificial Intelligence in Health Care

Computers can’t replace trained professionals, but through a collaboration between BWH and Massachusetts General Hospital, scientists hope that artificial intelligence technologies can improve the precision and efficiency of their research

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From Inspiration to Reality: How a Smartphone Test for Male Infertility Took Shape

Investigators have developed a male infertility test that users can perform with a smartphone. Find out how the Brigham Innovation Hub (iHub) in collaboration with Partners Innovation and clinical and entrepreneurial experts helped kindle a spark of innovation into a flame.

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Children at Risk: A Health Economist Measures the Prevalence and Economic Impact of Poverty or Stunting

For Chunling Lu, PhD, joining the Lancet Series on Early Child Development was a natural extension to her previous research activities, and she tells CRN that it has been one of the most inspiring experiences in her research career.

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Approaching Truth: Clinical Trials Test What We Think We Know

Clinical trials measure how living, human bodies – particularly sick and injured ones – respond to interventions. BWH has 1,500 PIs leading research teams and trials in virtually every area of medicine.

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What’s New in Research

"What's New in Research" sheds light on new work by Aditi Hazra, PhD, MPH, Katarzyna Karwacz, PhD, and Francisco Marty, MD.

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Investigating the Mysteries of a Rare Connective Tissue Disorder

During a trip to China in 2012, Paul Yu, MD, PhD, had the eye-opening experience of meeting patients with fibrodysplasia ossificans progressiva (FOP) for the first time at a specialty clinic at Shanghai Tongji Hospital.

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BWH Establishes Division of Medical Toxicology

This year, the Brigham will bring its own medical toxicologists directly to the bedside to share their expertise and care for patients facing adverse effects from medications, drug overdoses and substance abuse issues.

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Feeling Right at Home: Pilot Study Brings the Hospital Home

When patient William Terry, MD, was randomly selected to participate in a pilot study to receive care at home instead of being admitted to BWH, he didn’t think twice about signing up.

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Careers of the Future: Promising Professions in Research and Patient Care

BWHers share insights into what fields are growing and the trajectory of careers in biomedicine.

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BWH Researcher Devotes Life and Profession to Yoga

In addition to living in an ashram and practicing yoga several times per week, Sat Bir S. Khalsa, PhD, is a neuroscientist who studies yoga as an intervention for insomnia, anxiety and chronic stress.

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What’s New in Research

"What's New in Research" shares new work by Mallika Mendu, MD, MBA, Giovanni Traverso, MB, BChir, PhD, and Chuan Wu, PhD.

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New HHS, NIH Requirements on ClinicalTrials.gov Issued to Increase Transparency

Two important changes are going into effect on Wednesday, Jan. 18, in order to make information about clinical trials more transparent: the HHS final rule and the NIH policy.

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BRI Musculoskeletal Research Center Bridges Disciplines, Disorders

The Musculoskeletal Research Center connects researchers and clinicians pursuing research on bones, joints and muscles and the disorders that affect them.

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Careers of the Future: Promising Professions in Research and Patient Care

BWHers share insights into what fields are growing and the trajectory of careers in biomedicine.

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Searching for Answers in Inflammation

Learn more about the exciting research, collaborations and mentorship happening in the Serhan Lab in a new video.

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“Lab-in-a-Patient” Microdevices for Next-Generation Precision Medicine

Oliver Jonas, PhD, MA, has developed a tiny device, smaller than a grain of rice, that releases small doses of anti-cancer therapies into tumors.

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look who's talking

Look Who’s Talking: Pro Tips for Principal Investigators

This month, we asked: What do you wish you had known when you first started as a principal investigator at the Brigham?

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What’s New in Research

This month's edition of "What's New in Research" highlights exciting work by Charles N. Serhan, PhD, DSc, and Hadi Shafiee, PhD.

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Shyn Narrows in on More Effective Approach to Tumor Diagnosis and Treatment

Paul Shyn, MD, is exploring better ways to both diagnose and destroy tumors.

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Center for Surgery and Public Health Team Competes at Partners Connected Health Innovation Challenge

BWH team awarded Runner-Up, received more than $40,000 worth of supportive services for their innovative technology to screen and diagnose for peripheral artery disease

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A New Home for the Neurosciences

Neuroscience represents the biggest research area moving into the new Brigham building at 60 Fenwood Road this fall, and its clinicians and researchers plan to enhance communication and promote collaboration with many other departments.

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Koo, Savage Awarded Grants for Innovative Research Projects

Two projects awarded $50,000 grants from the BWH Health and Technology Innovation Fund during a ‘Shark Tank’-style competition to fund their respective projects.

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Multidisciplinary Surgery Offers Hope to Those Suffering From Pancreatitis

A daring technique, introduced in 1977, has been successfully performed six times at Brigham and Women’s hospital.

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What’s New in Research July 2016

Aspirin mobile app; nanoparticles and type 1 diabetes

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Taking Aim at Cancer’s Complexity

Aaron Goldman, PhD, a bioengineer by day and muay thai practitioner by night, is developing a 2-in-1 punch for knocking out cancer

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Building on Excellence: Cutting-Edge Technologies Available in the New Building

When the Brigham Building for the Future opens this fall, clinicians and researchers will have access to advanced tools and opportunities to collaborate and push the boundaries of discovery in ways that have never been possible before.

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Sex Differences Methods Workshop: Embracing a Sea of Change in Biomedical Research

Workshop offers advice, practical tips and historical context for new NIH requirements for female subjects in both basic and clinical research

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Gladyshev’s Quest to Understand Aging

BWH researcher studies aging and life span in naked mole rats, bats and more

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BWH Pathologists Pioneer Use of ‘Liquid Biopsies’ in Clinical Labs

Pathologists at the Brigham are leading the effort to bring liquid biopsies out of research labs and into clinical settings. These blood tests might enable more than half of lung cancer patients with a specific genetic mutation that indicates relapse to forego traditional, invasive surgical biopsies.

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BWH Cancer Experts Push Boundaries, Share Optimism at 2016 World Medical Innovation Forum on Cancer

Speakers shared innovations in prevention, detection and treatment of cancer

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The Future of Research: Improvements Planned for Thorn and 221 Longwood

Improvements to the Thorn research building are currently underway and a full engineering Facility Condition Assessment (FCA) of 221 Longwood has begun

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Infectious Disease Fellow Makes a Rapid Pivot From HIV to Zika

Thomas Rogers, MD, PhD, is searching for a better diagnostic and potential treatment for an emerging epidemic

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BWH Experts Forge Connections with Entrepreneurs to Drive Innovation

The Brigham Research Institute has partnered with the Massachusetts Biotechnology Council to facilitate collaborations between clinical and research experts at BWH and local biomedical startups

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A Multi-Pronged Approach to Understand and Treat Pulmonary Hypertension and Chronic Lung Disease in Infants

Neonatologist Helen Christou, MD, is conducting basic, clinical and translational research to find novel approaches for the prevention and treatment of pulmonary hypertension and chronic lung disease in newborns

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Brigham Building for the Future: Pulmonary Researchers Ready for Move into New Space

The second in a series about the Brigham Building for the Future, this story explores what the new building will mean for Pulmonary and Critical Care Medicine research

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BRIght Futures & Stepping Strong Winners: Where Are They Now?

Innovative prize winners from across BWH share updates on their projects

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What’s New in Research: April 2016

MicroRNA for Obesity and Diabetes; Zebrafish and the Immune System

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What’s New in Research: March 2016

Google Glass Meets Organs-On-Chips; Global Trends in Vaccine Discovery; Human Rights Failings in the Ebola Pandemic; A Promising Target for Glioblastoma Therapies

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Brigham Building for the Future: A Bright Future for Orthopaedic Collaboration

First in a series about the Brigham Building for the Future, this story explores what the new building will mean for basic research, clinical care and outcomes research for orthopaedics.

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Finding Biomarkers for Ovarian Cancer

Q&A with Shelley Tworoger, PhD, an epidemiologist in the BWH Channing Division of Network Medicine

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Bridging the Funding Gap

Investigators supported at critical funding junctures by the BRI’s Fund to Sustain Research Excellence have gone on to receive more than $300 million in NIH funding

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Stoklosa Devoted to Improving the Lives of Human Trafficking Victims

Hanni Stoklosa, MD, MPH, is deeply committed to improving the detection and care of human trafficking victims through her clinical care, national advocacy and international research.

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New Ventures in Biomedical Research Funding

The more than 3,100 investigators supported by Partners HealthCare have created more than 500 new inventions and 363 patents issued in fiscal year 2015.

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Policy and Innovation eValuation in Orthopedic Treatments (PIVOT) Center launched in BWH’s Department of Orthopedic Surgery

Research conducted by the PIVOT Center will help policy makers, physicians and patients to maximize treatment health benefits while reducing the overall economic burden of musculoskeletal diseases.

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MRCT Center Takes on Emerging Issues in Global Clinical Trials

The Multi-Regional Clinical Trials Center of BWH and Harvard is identifying and developing solutions to help global trials flourish while protecting participants.

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Life-long Passion for Nature, Outdoors Inspires Researcher

Q&A with Jessica Whited, PhD, a researcher in the BWH Regenerative Medicine Center

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Simple Solutions Spark Sweeping Changes in Medicine

Atul Gawande, MD, MPH, advocates for innovations to improve public health for people everywhere.

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Q&A with James Rathmell, MD

James Rathmell, MD, chair of the Department of Anesthesiology, Perioperative and Pain Medicine, discusses his first seven months at BWH, his goals for the department and how his diverse interests in medicine and photography have shaped his career path.

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What’s New in Research: January 2016

Atherosclerotic plaques; genetics and sleep; congenital heart disease and neurodevelopmental risk; treating toenail fungus; agonist versus surgery for prostate cancer

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Joining Forces to Conquer MS

In a groundbreaking new research collaboration, BWH has partnered with Google Life Sciences and Biogen to decipher why multiple sclerosis progresses so differently among individuals, and translate that information into new therapies and improved care.

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Imoigele Aisiku Focuses on Helping Patients Who Have Sustained Traumatic Brain Injuries

Emergency Department physician Imoigele Aisiku, MD, MBA, merges his research and clinical interests in traumatic brain injury and critical care at BWH.

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Gut Check: Studying the Gastrointestinal System to Find New Insights into Newborn Health

Catherine Gregory, PhD, RN, investigates the newborn gastrointestinal system in an effort to both prevent and better detect disease and enhance health in premature infants.

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Data from Electronic Health Records Power Research in Rheumatoid Arthritis

Elizabeth Karlson, MD, is using data from EHRs to answer pressing questions about rheumatoid arthritis.